The scalar-wave scattering by a rough anisotropic surface has been considered in the paper. In order to solve the problem, a two-scale model taking into account the wave scattering by coarse irregularities under the Kirchhoff’s approximation and determining that one by fine roughnesses through the Rayleigh method was used. The scattering cross section was averaged over the anisotropic distribution of the surface slopes. The results of numerical calculations of the total scattering cross section were presented. They demonstrate the anisotropy impact of the roughness distribution on the wave scattering indicatrix.