A spatial structure model of the complex formed by methionine-sulfoxide reductase B1 and thioredoxin in mouse redox system

Biophysics and medical physics

On the basis of data obtained by protein docking and refined by molecular dynamics technique, we have built a spatial model of complex formed by MsrBl and Trx mouse proteins. Protein interaction is facilitated by formation of intermolecular P-sheet, that results in disulfide bond stretching in oxidized state of MsrBl.