Mathematical modeling of determination of “Premeltons” sites in DNA by ultra short laser pulses

The article discusses a method for analyzing the structure of a molecule using ultrashort laser pulses (USP). A premelton or elongation in the structure of a molecule was chosen as a sample for theoretical modeling of the interaction of a laser pulse with a substance. A premelton is a region of a molecule in which the distance between two adjacent nitrogenous bases is increased. The study of such structures is interesting for limiting the parameters of DNA denaturation, since the process of separation of the molecule begins with the elongation region. At the moment, the study of such features of the DNA structure is difficult, electrophoresis and staining methods cannot always give an accurate result, especially on short sections of the molecule. In this paper, we theoretically model the results of the interaction of USP with a molecule in two cases, when elongation takes place and when the molecule is ideal. The results obtained show the expediency of using laser pulses as a method for determining the structure of a complex polyatomic object.