This paper is devoted to the investigation of laser cleaning of organic pigments on paper. In recent years, laser technologies have been widely used in the preservation of Cultural Heritage (CH). One of the main fields of laser application in this area is the cleaning of CH objects from various contaminations of natural or anthropogenic origin. Experimental results of laser cleaning with the Ytterbium pulsed fibre laser (1064 nm wavelength) of model samples of modern organic pigments on paper as well as Raman spectroscopy analysis of the obtained results are presented.