Autostainer feature for multielectrode arrays: proof-of-concept

Biophysics and medical physics
Authors:
Abstract:

Today, bioelectronics technologies are opening new horizons and paving the way for future development using a wide range of materials. For example, numerous purely electronic materials, such as silicon, textolite and various  polymer masks, are very promising for the purposes of cellular bioelectronics in vitro, but their optical properties limit their use, since modern microscopic control is still the most reliable tool for live cell diagnostics. This problem can  be solved with the help of special dyes, however the staining procedure requires reagents and time, which on an industrial scale will lead to costs and a slowdown in the production process. Here we propose a solution to this issue  based on the fabrication of cell-based bioelectronic devices that automatically stain cells without any additional sample manipulation.